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KMID : 1103720100620060585
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Journal of the Korean Society of Radiology
2010 Volume.62 No. 6 p.585 ~ p.591
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Comparison of Diffusion Weighted Imaging and Contrast Enhanced Imaging on MRI for Breast Lesions
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Choi Jae-Jung
Yim Hyeon-Woo
Cha Eun-Suk
Kim Sung-Hun
Jeong Seung-Hee
Kang Bong-Joo
Lee Jee-Hye
Jeh Su-Kyung
Park Yong-Gou
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Abstract
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Purpose: To retrospectively compare the MRI findings of diffusion-weighted imaging (DWI) and contrast-enhanced imaging (CEI) of breast lesions.
Materials and Methods: From June 2005 to June 2007, 159 patients with 159 biopsy-proven breast lesions underwent breast MRIs including DWI and CEI. Two breast imaging radiologists reviewed the MRI findings by consensus for the presence of a high signal intensity on DWI and enhancement on CEI. The MRI findings and concordance of DWI and CEI findings were correlated with the pathologic diagnosis.
Results: Of the 159 lesions 141 were malignant and 18 were benign. The sensitivity and specificity of DWI for detecting breast cancer was 96.5% (135/141) and 21.4% (5/18), respectively, compared to CEI, whose detection rate was 99.3% (140/141) and 33.3% (6/18), respectively. Larger lesions (> 1 cm) were more frequently detected by DWI. Of the enhanced malignancy, 96.4% (135/140) showed high signal intensity on DWI. The concordance of DWI and CEI findings in malignant lesions was significantly higher than benign lesions (95.7% vs. 61.1%, p<0.0001).
Conclusion: High signal intensity on diffuse-weighted MRI shows a high degree of sensitivity for detecting breast cancer.
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KEYWORD
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Diffusion, Breast Neoplasm, Magnetic Resonance Imaging
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